高冠斌，教授/博导，国家级高层次青年人才，湖北省青年拔尖人才，武汉理工大学材料复合新技术全国重点实验室研究员、神经退行性疾病纳米医药湖北省重点实验室副主任。主要研究方向是纳米生物医药材料，近五年主持科研项目12项，包括国家科技人才专项青年项目1项，国家自然科学基金项目3项(面上2+青年1)，湖北省青年拔尖人才项目1项，湖北省自然科学基金项目2项（面上1+青年1）；以第一/通讯作者在J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Natl. Sci. Rev.、Adv. Funct. Mater.、Nano Lett.等国际顶级期刊上发表SCI论文50余篇；授权中国发明专利7件，澳大利亚发明专利1件。先后入选湖北省青年拔尖人才（2023年）和国家万人计划青年拔尖人才（2024年），兼任湖北省药品注册审评专家、湖北省医疗器械注册审评专家，Interdisciplinary Materials期刊学术编辑和Journal of Integrative Neuroscience、Brain-X等期刊青年编委。

2025/01-至今 武汉理工大学材料复合新技术全国重点实验室 教授/博导

1. 国家高层次人才特殊支持计划青年项目，2025/01-2027/12，210万，在研，主持

54.  Jin Chen^#, Guanbin Gao^#,*, Zijun Zhang, Taolei Sun, Zhengyi Fu*, Zhaoyong Zou*, Nanocluster induced liquid-like precursor formation and crystallization: in situ visualization and 3D reconstruction, Journal of the American Chemical Society, 2025, 147(11), 9590–9600.

53.  Zijun Zhang, Limei Qian, Nan Zhang, Xiaobing Gao, Taolei Sun, Guanbin Gao*, Engineering A Non-Antibiotic Biomimetic Nano-Urchin for Broad-Spectrum and Long-Acting Antibacterial Spraying, Advanced Functional Materials, 2025, 35, 2501119.

52.  Qingxue Mu^#, Guanbin Gao^#,*, Zijun Zhang, Bin Zhang, Zhenhua Gu, Xinglin Liu, Liangchong Yu, Lei Shen*, Taolei Sun*, A validated criterion for engineering 0D@2D nanocomposite to modulate amyloid peptide self-assembly and fibril disassembly, Chemical Engineering Journal, 2025, 507, 160577. 

51.  Bin Zhang, Qingxue Mu, Ye Pei, Siyu Hu, Shuo Liu, Taolei Sun*, Guanbin Gao*, Synthesis strategies and multi-filed applications of nanoscale high-entropy alloys, Nano-Micro Letters, 2025, 17, 283. 

50.  Bin Zhang, Shuo Liu, Hao Deng, Ye Pei, Qingxue Mu, Yuming Lei, Taolei Sun*, Guanbin Gao*, Dumbbell-Shaped Au@CeO₂ Metal-Semiconductor Heteronanocrystals for Photothermal Catalysis of Organophosphate Degradation, Inorganic Chemistry, 2025, 64, 9, 4638-4643. 

49.  Shuquan Lv, Boran Li, Yinghui Li, Siyu Hu, Meng He, Taolei Sun, Guanbin Gao*, Refined phosphatidylcholine from soybean lecithin: Purification, molecular species identification, and antioxidant activity evaluation, LWT - Food Science & Technology, 2025, 225, 117704.

48.  Zehui Yao^#, Shasha Zhang^#*, Zijun Zhang, Quan Wan, Taolei Sun, Guanbin Gao*, Effect of Ligand Length on Antibacterial Activity of Ultra-small Gold Nanoparticles, ACS Materials Letters, 2025, 7(4), 1520-1525. 

47.  Shuquan Lv, Taolei Sun, Jingli Zhang, Yinghui Li, Shasha Zhang*, Guanbin Gao*, Adsorption behavior and mechanism of aqueous organic contaminants on β-cyclodextrin polymer, Environmental Research, 2025, 275, 121435.

46.  Xinyu Zhang, Xuan Zhou, Quan Wan, Taolei Sun, Guanbin Gao*, A smartphone sensing colorimetric detection of ascorbic acid in fruit samples based on Cu₂Fe(CN)₆@PVP nanozyme, Talanta, 2025, 293, 128152.

45.  Xuan Zhou, Xinyu Zhang, Zhenhua Gu, Quan Wan, Taolei Sun, Guanbin Gao*, Engineering Fe_1-xS/Cu₃(PO₄)₂ inorganic hybrid nanoflowers for rapid colorimetric detection of H₂O₂ and glucose, Microchemical Journal, 2025, 209, 112679.

44.  Zijun Zhang^#, Limei Qian^#, Nan Zhang^#, Xinyue Wang, Yunshen Fu, Guanbin Gao*, Taolei Sun*, Advances in Spiky Antibacterial Materials: From Bioinspired Design to Application, Small Structures, 2025, 6(1), 2400370.

43.  Yongqi Bai, Xingrui Qi, Hanjing Li, Yihui Ban, Rong Zhao, Yian Wang, Jingli Zhang*, Taolei Sun Guanbin Gao*, Pd-catalyzed domino Heck cyclization/cross-coupling of indoles with β-chlorovinyl ketones: synthesis of furan-bearing indolo[2,1-α]isoquinolines with antifungal activity, Organic & Biomolecular Chemistry,2025, 23, 3307–3313.

42.  Yuzhou Deng^#, Guanbin Gao^#,*, Liangchong Yu, Zijun Zhang, Bin Zhang, Hu Li, Xinyu Zhang, Lei Shen, Taolei Sun*, Engineering Core/Ligands Interfacial Anchors of Nanoparticles for Efficiently Inhibiting Both Aβ and Amylin Fibrillization, Small, 2024, 20, 2312046.

41.  Shuai Gong, Guanbin Gao*, Taolei Sun*, Lei Shen*, Inhibition of a-Synuclein Misfolding into β-Sheet Domains on Medium-Sized Gold Nanoclusters: Evidence from Enhanced Sampling MD Simulations, ACS Macro Letters, 2024, 13, 1476-1482.

40.  Hu Li^#, Guanbin Gao^#,*, Liangchong Yu, Zijun Zhang, Bin Zhang, Yuzhou Deng, Qingxue Mu, Lei Shen*, Taolei Sun*, Interfacial metal atoms of metallic nano-chaperones on modulating amyloid fibrillation, Science China Materials, 2024, 67(7), 2345-2354. 

39.  Furong Li^#, Ye Yuan^#, Donghao Lyu, Yujie Yi, Jingli Zhang*, Taolei Sun, Guanbin Gao*, Palladium-Catalyzed Domino Heck/Cross-Coupling Cyclization Reaction: Diastereoselective Synthesis of Furan-Containing Indolines, Journal of Organic Chemistry, 2024, 89, 11, 7552-7560.

38.   Linlin Yuan^#, Zhenhua Gu^#, Jingli Zhang^#, Zijun Zhang, Quan Wan, Liangchong Yu, Qingxue Mu, Taolei Sun, Guanbin Gao*, A pentametallic high-entropy mixed-dimensional mesoporous heterostructure for azo-dye wastewater degradation and decolorization, Separation and Purification Technology, 2024, 350,127951. 

37.  Zehui Yao, Zijun Zhang, Jingli Zhang, Jing Li, Guanbin Gao*, Taolei Sun*, Charge Effect of Mercaptobenzimidazole-Modified Ultrasmall Gold-Nanoparticles against Drug-Resistant Bacteria, ACS Applied Bio Materials, 2024, 7, 3330−3336.

36.  Zhenhua Gu, Jingli Zhang, Zijun Zhang, Qingxue Mu, Liangchong Yu, Taolei Sun*, Lei Shen*, Guanbin Gao*, Interfacial charge effects of supported-metal-clusters heterostructure on azo hydrogenation catalyzation, Nano Research, 2024,17(5),3853-3862. 

35.  Jingli Zhang, Weipeng Xu, Du Wang, Ye Yuan, Yongqi Bai, Minyan Wang*, Guanbin Gao*, Taolei Sun*, Divergent reactivity of Acrylamides and β-Chloroenones under Base-Controlled Palladium Catalysis: Construction of Spirooxindoles and Furan-containing 3,3-Disubstituted Oxindoles, Organic Chemistry Frontiers, 2024, 11(2), 348-357.

34.  Bin Zhang, Guanbin Gao*, Zijun Zhang, Baisheng Cao, Taolei Sun*, Ligand steric effects of nano-inhibitors on Aβ fibrillation at the nano-bio interfaces, Applied Surface Science, 2023, 640, 158427.

33.  Lin Zhou, Guanbin Gao*, Zhongjie Ma, Zijun Zhang, Zhenhua Gu, Liangchong Yu, Xiaohan Li, Nan Zhang, Limei Qian, Zelin Tao and Taolei Sun*, Gold Nanoclusters Enhance the Efficacy of the Polymer-Based Chaperone in Restoring and Maintaining the Native Conformation of Human Islet Amyloid Polypeptide, ACS Applied Materials & Interfaces, 2023, 15(2),3409-3419. 

32.  Wenrui Chen^#, Boran Li^#, Guanbin Gao*, Taolei Sun*, Chiral supramolecular nanomaterials: From chirality transfer and amplification to regulation and applications, Interdisciplinary Materials 2023, 2, 689-713.

31.  Hao Deng, Zhenhua Gu, Wenshan Zheng, Taolei Sun, Guanbin Gao*, Engineering Dumbbell-Shaped Au Nanobipyramid/Ag-CeO2 Plasmonic Bimetal-Semiconductor Heterostructures for Nitroaromatic Reduction. ACS Applied Nano Materials, 2023, 6(13), 11581-11589.

30.  Baisheng Cao, Guanbin Gao*, Jingli Zhang, Zijun Zhang, Taolei Sun*, A smartphone-assisted colorimetric sensor based on Fe1-xS nanozyme for detection of glucose and ascorbic-acid in soft drinks. Microchemical Journal, 2023, 193, 109018.

29.  Chengye Chen, Yilu Zeng, Guanbin Gao*, Taolei Sun*, and Lei Shen*, Flexibility Analysis of DNA Nanotubes with Prescribed Circumferences and Their Pearl-Necklace Assemblies with Gold Nanoclusters. Langmuir, 2023, 39, 9850-9856.

28.  郑文山, 高冠斌*, 邓浩, 孙涛垒*. Ag2Se@Ag2S核壳量子点的室温合成及其近红外荧光性能优化[J], 化学学报, 2023, 81(7), 763-770.

27.  Guanbin Gao*, Xinglin Liu, Zhenhua Gu, Qingxue Mu, Guowei Zhu, Ting Zhang, Cheng Zhang, Lin Zhou, Lei Shen* and Taolei Sun*, Engineering Nanointerfaces of Au25-Clusters for Chaperone-Mediated Peptide Amyloidosis, Nano Letters, 2022, 22, 2964-2970.

26.  Guanbin Gao*, Guowei Zhu, Liangchong Yu, Zijun Zhang, Ting Zhang, Xinglin Liu, Cheng Zhang, Lin Zhou and Taolei Sun*, Chiral effect on Aβ fibrillation from molecular-scale to nanoscale, Nano Research, 2022, 15(7), 6721-6729.

25.  Guanbin Gao*, Ting Zhang, Wenkang Zhang, Zhuoying Luo, Zijun Zhang, Zhenhua Gu, Liangchong Yu, Qinxue Mu and Taolei Sun*, High Efficiency and Related Mechanism of Au(RC) Nanoclusters on Disaggregating Aβ fibrils, Journal of Colloid and Interface Science, 2022, 621, 67-76. 

24.  Cheng Zhang^#, Xiaobing Gao^#, Wenrui Chen^#, Meng He, Yao Yu, Guanbin Gao*, Taolei Sun*, Advances of Gold Nanoclusters for Bioimaging, iScience, 2022, 25, 105022.

23.  Meng He^#, Jing Yao^#, Zijun Zhang^#, Ying Zhang, Rui Chen, Zhenhua Gu, XuFeng Huang, Chao Deng, Ruqin Zhou, Jun Fan, Baohua Zhang, Yanqian Xie, Guanbin Gao* and Taolei Sun*, Gold nanoclusters eliminate obesity induced by antipsychotics, Scientific Reports, 2022, 12, 5502. 

22.  Jun Fan, Ruqin Zhou, Meng He*, Ruoxi Li, Yufeng Zuo, Benben Li, Guanbin Gao* and Taolei Sun*, The role of hypothalamic endoplasmic reticulum stress in schizophrenia and antipsychotic-induced weight gain: A narrative review. Frontiers in Neuroscience, 2022, 16, 947295.

21.  Jianhang Li, Guanbin Gao*, Xintong Tang, Meng Yu, Meng He and Taolei Sun*, Isomeric Effect of Nano-Inhibitors on Aβ₄₀ Fibrillation at The Nano-Bio Interface, ACS Applied Materials & Interfaces, 2021, 13, 4, 4894-4904. 

20.  余梦, 张子俊, 朱国委, 谷振华, 段玉霖, 余良翀, 高冠斌*, 孙涛垒*. Ag2S基近红外II区荧光量子点的水相合成优化探究[J], 化学学报, 2021, 79(10): 1281-1285.

19.  Wenkang Zhang, Guanbin Gao*, Zhongjie Ma, Zhuoying Luo, Meng He and Taolei Sun*, Au₂₃(CR)₁₄ Nanocluster Restores Fibril Aβ’s Unfolded State with Abolished Cytotoxicity and Dissolves Endogenous Aβ Plaques, National Science Review, 2020, 7(4), 763-774.

18.  Xintong Tang, Guanbin Gao*, Ting Zhang, Jianhang Li, Meng Yu, Meng He and Taolei Sun*, Charge Effects at Nano-Bio interfaces: A Model of Charged Gold Nanoclusters on Amylin Fibrillation, Nanoscale, 2020, 12, 18834-18843. 

17.  Zhuoying Luo, Guanbin Gao*, Zhongjie Ma, Qian Liu, Xiaobing Gao, Xintong Tang, Zhenxing Gao, Chaoyang Li* and Taolei Sun*, Cichoric Acid from Witloof Inhibit Misfolding Aggregation and Fibrillation of hIAPP, International Journal of Biological Macromolecules, 2020, 148, 1272-1279.

16.  Wenkang Zhang, Meng Yu, Wenbo Zhu, Liang Wang, Juncheng Wang, Feifei Yang, Jing Li, Guanbin Gao*, Temperature-Controlled β-Crystal-to-α-Crystal Phase Transition of HgS Nanoparticles, Journal of Nanoscience and Nanotechnology, 2020, 20(4), 2567-2572;

15.  Jinqi Hu, Guanbin Gao*, Meng He*, Qiang Yin, Xiaobing Gao, Haixing Xu, and Taolei Sun*, The Optimal Route of Gold Nanoclusters Administration in Mice Targeting Parkinson’s Disease, Nanomedicine, 2020, 15(6), 563-580.

14.  王君诚, 杨菲菲, 高冠斌*, 孙涛垒*, Ag掺杂HgS量子点: 一种pH调谐的近红外Ⅱ区荧光纳米探针, 无机材料学报, 2019, 34(11), 1156-1160.

13.  Zhongjie Ma, Guanbin Gao*, Zhuoying Luo, Xintong Tang and Taolei Sun*, Tuning Chirality Transfer and Amplification of Supraparticles via Solvent Inducing Self-aggregation of Chiral Gold Nanoclusters, Journal of Physical Chemistry C, 2019, 123, 24973-24978.

12.  Jing Li, Rui Chen, Shasha Zhang, Zhongjie Ma, Zhuoying Luo, Guanbin Gao*, Chiral Effect at Nano-Bio Interface: A Model of Chiral Gold Nanoparticle on Amylin Fibrillation, Nanomaterials, 2019, 9(3), 412.

11.  Juncheng Wang, Guanbin Gao*, Feifei Yang, Rui Chen, Liang Wang, Wenbo Zhu, Zhongjie Ma, Zhuoying Luo and Taolei Sun*, A Fluorescent Nanoprobe Based on HgS/ZnS Core/Shell Quantum Dots for In-Situ Rapid Visual Detection of Cr³⁺, Journal of Nanoparticle Research, 2019, 21(3), 50.

10.  Feifei Yang, Guanbin Gao*, Juncheng Wang, Rui Chen, Wenbo Zhu, Liang Wang, Zhongjie Ma, Zhuoying Luo and Taolei Sun*, Chiral β-HgS Quantum Dots: Aqueous Synthesis, Optical Properties and Cytocompatibility, Journal of Colloid and Interface Science, 2019, 537, 422-430.

9.   Guanbin Gao, Rui Chen, Meng He, Jing Li, Jing Li, Liyun Wang and Taolei Sun*. Gold Nanoclusters for Parkinson’s Disease Treatment, Biomaterials, 2019, 194, 36-46.

8.    Shan Wu, Guanbin Gao*, Shasha Zhang, Wenbo Zhu, Liang Wang, Rui Chen, Wenkang Zhang, Juncheng Wang, Feifei Yang; Jing Li, Lei Shen, Taolei Sun*, Mixed-solvent precipitation: a facile approach for nanoparticle self-assembled monolayers, Applied Surface Science, 2019, 465, 526-531.

7.  刘康, 高冠斌*, 孙涛垒*, β-HgS 量子点的制备、性质及应用[J], 化学进展, 2017, 29, 776-784.

6.  胡雪娇, 高冠斌*, 张明曦*, 金纳米棒——从可控制备与修饰到纳米生物学与生物医学应用[J]，物理化学学报, 2017, 33, 1324-1337.

5.   Guanbin Gao, Mingxi Zhang, Dejun Gong, Rui Chen, Xuejiao Hu and Taolei Sun*. The size-effect of gold nanoparticles and nanoclusters in the inhibition of amyloid-β fibrillation. Nanoscale, 2017, 9, 4107-4113.

4.  Xuesong Lv, Zhixiong Huang*, Mingxian Shi*, Yun Fan, Guanbin Gao*, Composition Distribution, Damping and Thermal Properties of the Thickness-Continuous Gradient Epoxy/Polyurethane Interpenetrating Polymer Networks, Applied Science-Basel, 2017, 7, 135.

3.  高冠斌，龚德君，张明曦*，孙涛垒*，手性金纳米团簇：一种新型近红外荧光探针，化学学报，2016，74，363-374. 

2.   Xuesong Lv*, Zhixiong Huang*, Minxian Shi, Yun Fan, Guanbin Gao*, Self-gradient mechanism, morphology and damping analysis of a thickness continuous gradient epoxy-polyurethane interpenetrating polymer network, RSC Advances, 2016, 6, 111688-111701.

1.   Guanbin Gao, Mingxi Zhang, Pei Lu, Guanlun Guo, Dong Wang and Taolei Sun*. Chirality-assisted ring-like aggregation of Aβ(1-40) at liquid-solid interfaces: a stereoselective two-step assembly process. Angewandte Chemie International Edition, 2015, 54, 2245-2250.