李胜辉
李胜辉 武汉理工大学外聘教授 硕/博导
李胜辉，武汉理工大学外聘教授，博导。主要研究方向为肠道微生物与疾病、人体微生物组、新一代益生菌和有益微生物制剂、微生物组新技术与新方法等。目前已有90余篇论文在Nature、Nature communications、Gut、Advanced science、Genome biology、Cell、Microbiome、Nature microbiology、Genome medicine等高水平“SCI”期刊上发表；论文总影响因子累积>700，总引用数>13000次，入选“全球前2%高被引科学家”名单。长期担任多个国际期刊特约编委，编辑及审稿人。团队获得软件著作权60余项，中国及国际专利12项，多次参与国家自然科学基金及省市级基金项目。
研究领域
①肠道微生物与疾病（自身免疫病，代谢性疾病，慢性病等）
②人体微生物组（口腔，生殖道微生物）
③新一代益生菌和有益微生物制剂
④微生物组新技术与新方法（代谢组，病毒组，微生态医疗等）
代表论文
1. Yan Q, Huang L, Li S#, et al. The Chinese gut virus catalogue reveals gut virome diversity and disease-related viral signatures [J]. Genome Medicine, 2025, 17 (1): 30-30.
2. Li S#, Zhang P, Guo R, Ma S, et al. A metagenome-wide study of the gut virome in chronic kidney disease [J]. Theranostics, 2025, 15(5): 1642.
3. Yan Q, Li S#, Yan Q, et al. A genomic compendium of cultivated human gut fungi characterizes the gut mycobiome and its relevance to common diseases. [J]. Cell, 2024, 187 (12): 2969-2989.e24.
4. Sun W, Zhang Y, Li S*, et al. A population-scale analysis of 36 gut microbiome studies reveals universal species signatures for common diseases [J]. npj Biofilms and Microbiomes, 2024, 10 (1): 96-96.
5. Li S#, Tian X, Li S, Wang C, et al. Gut virome-wide association analysis identifies cross-population viral signatures for inflammatory bowel disease [J]. Microbiome, 2024, 12(1): 130.
6. Li S#, Chen, Chen, et al. "Genomic landscape in the human vaginal microbiome links to host geographics and genetics." (2024).
7. Jianjun L, Qiulong Y, Li S#, et al. Integrative metagenomic and metabolomic analyses reveal the potential of gut microbiota to exacerbate acute pancreatitis [J]. npj Biofilms and Microbiomes, 2024, 10 (1): 29-29.
8. Huang L, Guo R, Li S*, et al. A multi-kingdom collection of 33,804 reference genomes for the human vaginal microbiome. [J]. Nature microbiology, 2024, 9 (8): 2185-2200.
9. Li S#, Zhang, Pan, et al. "Metagenome-wide analysis uncovers gut microbial signatures and implicates taxon-specific functions in end-stage renal disease." Genome Biology 24.1 (2023): 226.
10. Li S*, et al. "A catalog of 48,425 nonredundant viruses from oral metagenomes expands the horizon of the human oral virome." Iscience 25.6 (2022).
11. Li S#, Li, Jing, et al. "Tonsillar Microbiome‐Derived Lantibiotics Induce Structural Changes of IL‐6 and IL‐21 Receptors and Modulate Host Immunity." Advanced Science 9.30 (2022): 2202706.
12. Guangyang W, Li S#, Qiulong Y, et al. Optimization and evaluation of viral metagenomic amplification and sequencing procedures toward a genome-level resolution of the human fecal DNA virome. [J]. Journal of advanced research, 2022, 48 75-86.
13. Fang C, Li S#, Ruochun G, et al. Meta-analysis of fecal viromes demonstrates high diagnostic potential of the gut viral signatures for colorectal cancer and adenoma risk assessment. [J]. Journal of advanced research, 2022, 49 103-114.
14. Hao J, Lijun Y, Li S#, et al. Hybrid, ultra-deep metagenomic sequencing enables genomic and functional characterization of low-abundance species in the human gut microbiome. [J]. Gut microbes, 2022, 14 (1): 2021790-2021790.
15. Xiaokui H, Li S#, Fan W, et al. Cultivated human intestinal fungus Candida metapsilosis M2006B attenuates colitis by secreting acyclic sesquiterpenoids as FXR agonists. [J]. Gut, 2022, 71 (11):
16. Zheng, Ning, Li S#, et al. "Comparison of the gut microbiota of short-term and long-term medical workers and non-medical controls: a cross-sectional analysis." Clinical Microbiology and Infection 27.9 (2021): 1285-1292.
17. Yan, Qiulong, Li S*, et al. "Characterization of the gut DNA and RNA viromes in a cohort of Chinese residents and visiting Pakistanis." Virus Evolution 7.1 (2021): veab022.
18. Li S#, Wang, Xifan, et al. "Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents." Gut 69.12 (2020): 2131-2142.
19. Hongling Y, Li S*, Shaochuan L, et al. Systematic analysis of gut microbiota in pregnant women and its correlations with individual heterogeneity. [J]. NPJ biofilms and microbiomes, 2020, 6 (1): 32-32.
20. Sun, Jian, Li S#, et al. "Environmental remodeling of human gut microbiota and antibiotic resistome in livestock farms." Nature communications 11.1 (2020): 1427.
